| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S4MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000IHC-P:1:200-1:800ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PBRM1 |
| Gene ID: | 55193 |
| Uniprot ID: | PB1_HUMAN |
| Immunogen Region: | 530-680 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 530-680 of human PBRM1 (Q86U86). |
| Immunogen Sequence: | VLEAREPGSGRRLCDLFMVK PSKKDYPDYYKIILEPMDLK IIEHNIRNDKYAGEEGMIED MKLMFRNARHYNEEGSQVYN DAHILEKLLKEKRKELGPLP DDDDMASPKLKLSRKSGISP KKSKYMTPMQQKLNEVYEAV KNYTDKRGRRL |
| Tissue Specificity | Widely expressed. |
| Function | Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. |
| Protein Name | Protein Polybromo-1Hpb1Brg1-Associated Factor 180Baf180Polybromo-1d |
| Database Links | Reactome: R-HSA-3214858Reactome: R-HSA-8939243 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Protein Polybromo-1 antibodyAnti-Hpb1 antibodyAnti-Brg1-Associated Factor 180 antibodyAnti-Baf180 antibodyAnti-Polybromo-1d antibodyAnti-PBRM1 antibodyAnti-BAF180 antibodyAnti-PB1 antibody |
Information sourced from Uniprot.org
