Anti-Papillomavirus type 1 E2-protein antibody (210-410 aa) [3H5] (STJA0002815)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG
STJA0002815
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General Information

Short DescriptionMouse monoclonal anti-Papillomavirus type 1 E2-protein (210-410 aa) for use in ELISA and IF in PV samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsELISA/IF
HostMouse
ReactivityPV
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone ID3H5
IsotypeIgG
ConjugationUnconjugated
PurificationProtein A purification
Dilution RangeELISA-0.1 to 0.2 µg/ml; IF 0.5 to 20 µg/ml This is a conformational antibody and does not work in WB or other denaturative conditions. This antibody blocks E1-E2 dependent replication origin complex formation, dissociates protein/DNA complex and ther
FormulationPBS with 50% glycerol
Storage InstructionStore at-20 or-70 °C upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles as product degradation may result.

Target Information

Immunogen Region210-410 aa

Additional Info

Background E2 protein plays a central role in the viral life cycle as it regulates both transcription and replication of the viral genome. Can either activate or repress transcription. The E1-E2 protein complex binds to the origin of DNA replication activating replication of the BPV

Information sourced from Uniprot.org

Citations

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