| Short Description : | Rabbit polyclonal PAPD4 (1-300) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TENT2 |
| Gene ID: | 167153 |
| Uniprot ID: | GLD2_HUMAN |
| Immunogen Region: | 1-300 |
| Immunogen Sequence: | MFPNSILGRPPFTPNHQQHN NFFTLSPTVYSHQQLIDAQF NFQNADLSRAVSLQQLTYGN VSPIQTSASPLFRGRKRLSD EKNLPLDGKRQRFHSPHQEP TVVNQIVPLSGERRYSMPPL FHTHYVPDIVRCVPPFREIA FLEPREITLPEAKDKLSQQI LELFETCQQQISDLKKKELC RTQLQREIQLLFPQSRLFLV GSSLNGFGTRSSDGDLCLVV KEEPCFFQVNQKTEARHIL |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PAPD4 (NP_776158.2). |
| Tissue Specificity | Expressed in brain. Within brain, it is expressed in cerebellum, hippocampus and medulla. |
| Function | Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Does not play a role in replication-dependent histone mRNA degradation. Adds a single nucleotide to the 3' end of specific miRNAs, monoadenylation stabilizes and prolongs the activity of some but not all miRNAs. |
| Protein Name | Poly(A Rna Polymerase Gld2Hgld-2Pap-Associated Domain-Containing Protein 4Terminal Nucleotidyltransferase 2Terminal Uridylyltransferase 2Tutase 2 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Poly(A Rna Polymerase Gld2 antibodyAnti-Hgld-2 antibodyAnti-Pap-Associated Domain-Containing Protein 4 antibodyAnti-Terminal Nucleotidyltransferase 2 antibodyAnti-Terminal Uridylyltransferase 2 antibodyAnti-Tutase 2 antibodyAnti-TENT2 antibodyAnti-GLD2 antibodyAnti-PAPD4 antibody |
Information sourced from Uniprot.org
