• Western blot analysis of lysate from Jurkat cells, using PAI-1 antibody.
  • Western blot analysis of Jurkat cells using PAI-1 Polyclonal Antibody
  • Immunohistochemistry analysis of PAI-1 antibody in paraffin-embedded human brain tissue.
  • Western blot analysis of various cells using PAI-1 Polyclonal Antibody

Anti-PAI-1 antibody (STJ94934)

SKU:
STJ94934

Current Stock:
Host: Rabbit
Applications: WB, IHC-P, ELISA
Reactivity: Human, Mouse, Rat
Short Description: Rabbit polyclonal anti-PAI-1 antibody is suitable for use in Western Blot, Immunohistochemistry and ELISA.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.
Storage Instruction: Store at-20°C, and avoid repeat freeze-thaw cycles.
Concentration: 1 mg/ml
Isotype: IgG
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
Specificity: PAI-1 polyclonal antibody detects endogenous levels of PAI-1 protein.
Uniprot ID: PAI1_HUMAN
Gene ID: 5054
Gene Symbol: SERPINE1
Immunogen: Synthesized peptide derived from human PAI-1.
Immunogen Region: Internal
Post Translational Modifications Inactivated by proteolytic attack of the urokinase-type (u-PA) and the tissue-type (TPA), cleaving the 369-Arg-|-Met-370 bond.
Function Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis.
Protein Name Plasminogen Activator Inhibitor 1
Pai
Pai-1
Endothelial Plasminogen Activator Inhibitor
Serpin E1
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-1368108
Reactome: R-HSA-2173796
Reactome: R-HSA-3000178
Reactome: R-HSA-75205
Cellular Localisation Secreted
Alternative Antibody Names Anti-Plasminogen Activator Inhibitor 1 antibody
Anti-Pai antibody
Anti-Pai-1 antibody
Anti-Endothelial Plasminogen Activator Inhibitor antibody
Anti-Serpin E1 antibody
Anti-SERPINE1 antibody
Anti-PAI1 antibody
Anti-PLANH1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance