| Short Description : | Rabbit polyclonal anti-Phosphofurin acidic cluster sorting protein 2 (807-857 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:1000-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PACS2 |
| Gene ID: | 23241 |
| Uniprot ID: | PACS2_HUMAN |
| Immunogen: | Synthesized peptide derived from the human PACS2 at the amino acid range 807-857 |
| Immunogen Region: | 807-857 aa |
| Specificity: | This antibody detects endogenous levels of human PACS2 |
| Function | Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments. |
| Protein Name | Phosphofurin Acidic Cluster Sorting Protein 2Pacs-2Pacs1-Like Protein |
| Database Links | |
| Cellular Localisation | Endoplasmic ReticulumMitochondrion |
| Alternative Antibody Names | Anti-Phosphofurin Acidic Cluster Sorting Protein 2 antibodyAnti-Pacs-2 antibodyAnti-Pacs1-Like Protein antibodyAnti-PACS2 antibodyAnti-KIAA0602 antibodyAnti-PACS1L antibody |
Information sourced from Uniprot.org
