Anti-PACS2 antibody (807-857 aa) (STJ198058)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human PACS2 at the amino acid range 807-857
General Information
| Short Description | Rabbit polyclonal anti-Phosphofurin acidic cluster sorting protein 2 (807-857 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PACS2 |
| Gene ID | 23241 |
| Uniprot ID | PACS2_HUMAN |
| Immunogen | Synthesized peptide derived from the human PACS2 at the amino acid range 807-857 |
| Immunogen Region | 807-857 aa |
| Specificity | This antibody detects endogenous levels of human PACS2 |
Additional Info
| Function | Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments. |
| Protein Name | Phosphofurin Acidic Cluster Sorting Protein 2Pacs-2Pacs1-Like Protein |
| Database Links | |
| Cellular Localisation | Endoplasmic ReticulumMitochondrion |
| Alternative Antibody Names | Anti-Phosphofurin Acidic Cluster Sorting Protein 2 antibodyAnti-Pacs-2 antibodyAnti-Pacs1-Like Protein antibodyAnti-PACS2 antibodyAnti-KIAA0602 antibodyAnti-PACS1L antibody |
Information sourced from Uniprot.org