| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Phosphofurin acidic cluster sorting protein 2 (807-857 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PACS2 |
| Gene ID: |
23241 |
| Uniprot ID: |
PACS2_HUMAN |
| Immunogen Region: |
807-857 aa |
| Specificity: |
This antibody detects endogenous levels of human PACS2 |
| Immunogen: |
Synthesized peptide derived from the human PACS2 at the amino acid range 807-857 |
| Function | Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments. |
| Protein Name | Phosphofurin Acidic Cluster Sorting Protein 2Pacs-2Pacs1-Like Protein |
| Cellular Localisation | Endoplasmic ReticulumMitochondrion |
| Alternative Antibody Names | Anti-Phosphofurin Acidic Cluster Sorting Protein 2 antibodyAnti-Pacs-2 antibodyAnti-Pacs1-Like Protein antibodyAnti-PACS2 antibodyAnti-KIAA0602 antibodyAnti-PACS1L antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
