Anti-Otubain-2/OTUB2 antibody (1-234aa) [AT1F8] (STJA0041884)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenRecombinant human OTUB2 (1-234aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-Otubain-2/OTUB2 (1-234aa) for use in ELISA and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT1F8 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | OTUB2 |
| Gene ID | 78990 |
| Uniprot ID | OTUB2_HUMAN |
| Accession Number | NP_075601 |
| Immunogen | Recombinant human OTUB2 (1-234aa) purified from E. coli |
| Immunogen Region | 1-234aa |
Additional Info
| Tissue Specificity | Widely expressed. Expressed at higher level in brain. |
| Function | Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Mediates deubiquitination of 'Lys-11'-,'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains. |
| Protein Name | Ubiquitin Thioesterase Otub2Deubiquitinating Enzyme Otub2Otu Domain-Containing Ubiquitin Aldehyde-Binding Protein 2Otubain-2Ubiquitin-Specific-Processing Protease Otub2 |
| Database Links | Reactome: R-HSA-5689896 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ubiquitin Thioesterase Otub2 antibodyAnti-Deubiquitinating Enzyme Otub2 antibodyAnti-Otu Domain-Containing Ubiquitin Aldehyde-Binding Protein 2 antibodyAnti-Otubain-2 antibodyAnti-Ubiquitin-Specific-Processing Protease Otub2 antibodyAnti-OTUB2 antibodyAnti-C14orf137 antibodyAnti-OTB2 antibodyAnti-OTU2 antibody |
Information sourced from Uniprot.org