| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-OSBPL2 (291-480) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
OSBPL2 |
| Gene ID: |
9885 |
| Uniprot ID: |
OSBL2_HUMAN |
| Immunogen Region: |
291-480 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 291-480 of human OSBPL2 (NP_653081.1). |
| Immunogen Sequence: |
NKKKLFMIYGKWTECLWGID PVSYESFKKQERRGDHLRKA KLDEDSGKADSDVADDVPVA QETVQVIPGSKLLWRINTRP PNSAQMYNFTSFTVSLNELE TGMEKTLPPTDCRLRPDIRG MENGNMDLASQEKERLEEKQ REARRERAKEEAEWQTRWFY PGNNPYTGTPDWLYAGDYFE RNFSDCPDIY |
| Tissue Specificity | Widely expressed. |
| Function | Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane. Binds phosphoinositides, such as phosphatidylinositol-4,5-bisphosphate. Exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Binds cholesterol, dehydroergosterol, 22(R)-hydroxycholesterol and 25-hydroxycholesterol (in vitro). |
| Protein Name | Oxysterol-Binding Protein-Related Protein 2Orp-2Osbp-Related Protein 2 |
| Database Links | Reactome: R-HSA-192105 |
| Cellular Localisation | CytoplasmCytosolLipid DropletCell MembranePeripheral Membrane ProteinCytoplasmic SideDetected On The Surface Of Cytosolic Lipid DropletsRecruited To The Cell Membrane By Phosphatidylinositol-Phosphate Binding |
| Alternative Antibody Names | Anti-Oxysterol-Binding Protein-Related Protein 2 antibodyAnti-Orp-2 antibodyAnti-Osbp-Related Protein 2 antibodyAnti-OSBPL2 antibodyAnti-KIAA0772 antibodyAnti-ORP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
