Western blot analysis of various lysates using OSBPL2 Rabbit polyclonal antibody (STJ116433) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-OSBPL2 antibody (291-480) (STJ116433)

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STJ116433
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: OSBPL2
Gene ID: 9885
Uniprot ID: OSBL2_HUMAN
Immunogen Region: 291-480
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 291-480 of human OSBPL2 (NP_653081.1).
Immunogen Sequence: NKKKLFMIYGKWTECLWGID PVSYESFKKQERRGDHLRKA KLDEDSGKADSDVADDVPVA QETVQVIPGSKLLWRINTRP PNSAQMYNFTSFTVSLNELE TGMEKTLPPTDCRLRPDIRG MENGNMDLASQEKERLEEKQ REARRERAKEEAEWQTRWFY PGNNPYTGTPDWLYAGDYFE RNFSDCPDIY
Tissue Specificity Widely expressed.
Function Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane. Binds phosphoinositides, such as phosphatidylinositol-4,5-bisphosphate. Exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Binds cholesterol, dehydroergosterol, 22(R)-hydroxycholesterol and 25-hydroxycholesterol (in vitro).
Protein Name Oxysterol-Binding Protein-Related Protein 2
Orp-2
Osbp-Related Protein 2
Database Links Reactome: R-HSA-192105
Cellular Localisation Cytoplasm
Cytosol
Lipid Droplet
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Detected On The Surface Of Cytosolic Lipid Droplets
Recruited To The Cell Membrane By Phosphatidylinositol-Phosphate Binding
Alternative Antibody Names Anti-Oxysterol-Binding Protein-Related Protein 2 antibody
Anti-Orp-2 antibody
Anti-Osbp-Related Protein 2 antibody
Anti-OSBPL2 antibody
Anti-KIAA0772 antibody
Anti-ORP2 antibody

Information sourced from Uniprot.org

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