• Immunostaining of primary rat cortical neuroepithelial cells with anti-Olig2 (1538-OLIG2, red, 1:1000). The cells were treated with basic FGF for 30 hours prior to staining (this induces Olig2 expression in these primary cells).
  • An illustration differentiating mouse and human oligodendrocytes in the process of glial humanization of a mouse brain model used to study HIV-1 infection. Immunoflourescence of paraffin embedded chimeric mouse brain 5-µm thick tissue section immunolabeling oligodendrocytes with anti-OLIG2 antibody (1538-OLIG2, 1:500, green) and a human specific anti-nuclei antibody (clone 3E1. 3). The blue stain is DAPI. Images courtesy Larisa Poluektova, University of Nebraska Medical Center.
  • Western blot of neonatal rat brain lysate showing specific immunolabeling of the ~32 kDa Olig2 protein.
  • Immunostaining of Olig 2 in 3-month-old mouse brain Olig 2: Red; Nuclear: Blue. Image courtesy of Mengmeng Jin, Rutgers University.

Anti-OLIG2 antibody (STJA0003732)

SKU:
STJA0003732-100

£442.50
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Host: Rabbit
Applications: WB/IHC/ICC/IP
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Olig2 is suitable for use in Western Blot, Immunohistochemistry, Immunocytochemistry and Immunoprecipitation research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 100 µl in 100 mM Glycine, 200 mM Tris, pH 8.0
Purification: This antibody was protein a purified.
Dilution Range: WB 1:3000
IHC 1:200-1:1000
ICC 1:1000
IP 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Olig2
Gene ID: 50913
Uniprot ID: OLIG2_MOUSE
Immunogen: Recombinant mouse Olig2.
Tissue Specificity Expressed specifically in the brain.
Function Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Functions together with ZNF488 to promote oligodendrocyte differentiation. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development.
Protein Name Oligodendrocyte Transcription Factor 2
Oligo2
Cellular Localisation Nucleus
Cytoplasm
The Nls Contained In The Bhlh Domain Could Be Masked In The Native Form And Translocation To The Nucleus Could Be Mediated By Interaction Either With Class E Bhlh Partner Protein Or With Nkx2-2
Alternative Antibody Names Anti-Oligodendrocyte Transcription Factor 2 antibody
Anti-Oligo2 antibody
Anti-Olig2 antibody

Information sourced from Uniprot.org

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