Anti-OGFOD1 antibody (1-140) (STJ118970)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal OGFOD1 (1-140) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | OGFOD1 |
| Gene ID | 55239 |
| Uniprot ID | OGFD1_HUMAN |
| Immunogen Region | 1-140 |
| Immunogen Sequence | MNGKRPAEPGPARVGKKGKK EVMAEFSDAVTEETLKKQVA EAWSRRTPFSHEVIVMDMDP FLHCVIPNFIQSQDFLEGLQ KELMNLDFHEKYNDLYKFQQ SDDLKKRREPHISTLRKILF EDFRSWLSDISKIDLESTID |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human OGFOD1 (NP_060703.3). |
Additional Info
| Function | Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro-62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation. |
| Protein Name | Prolyl 3-Hydroxylase Ogfod12-Oxoglutarate And Iron-Dependent Oxygenase Domain-Containing Protein 1Termination And Polyadenylation 1 HomologUs12 Prolyl 3-Hydroxylase |
| Database Links | Reactome: R-HSA-9629569 |
| Cellular Localisation | Isoform 1: CytoplasmNucleusMainly NuclearA Portion Relocalizes To Cytoplasmic Stress Granules Upon StressIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Prolyl 3-Hydroxylase Ogfod1 antibodyAnti-2-Oxoglutarate And Iron-Dependent Oxygenase Domain-Containing Protein 1 antibodyAnti-Termination And Polyadenylation 1 Homolog antibodyAnti-Us12 Prolyl 3-Hydroxylase antibodyAnti-OGFOD1 antibodyAnti-KIAA1612 antibodyAnti-TPA1 antibody |
Information sourced from Uniprot.org