Host: |
Rabbit |
Applications: |
IHC/WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-2-oxoglutarate dehydrogenase-like, mitochondrial (C-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000IHC 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
OGDHL |
Gene ID: |
55753 |
Uniprot ID: |
OGDHL_HUMAN |
Immunogen Region: |
C-Term |
Specificity: |
This antibody detects endogenous levels of OGDHL at Human |
Immunogen: |
Synthesized peptide derived from human C-ternal OGDHL |
Function | 2-oxoglutarate dehydrogenase (E1-like) component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDHC) which mediates the decarboxylation of alpha-ketoglutarate in the tricarboxylic acid cycle. The OGDHC complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) while reducing NAD(+) to NADH. The OGDHC complex is mainly active in the mitochondrion. Involved in the inhibition of cell proliferation and in apoptosis. |
Protein Name | 2-Oxoglutarate Dehydrogenase-Like - Mitochondrial2-Oxoglutarate Dehydrogenase Complex Component E1-LikeOgdc-E1-LikeAlpha-Ketoglutarate Dehydrogenase-Like |
Cellular Localisation | Mitochondrion Matrix |
Alternative Antibody Names | Anti-2-Oxoglutarate Dehydrogenase-Like - Mitochondrial antibodyAnti-2-Oxoglutarate Dehydrogenase Complex Component E1-Like antibodyAnti-Ogdc-E1-Like antibodyAnti-Alpha-Ketoglutarate Dehydrogenase-Like antibodyAnti-OGDHL antibodyAnti-KIAA1290 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance