| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-2-oxoglutarate dehydrogenase-like, mitochondrial (C-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | OGDHL |
| Gene ID: | 55753 |
| Uniprot ID: | OGDHL_HUMAN |
| Immunogen Region: | C-Term |
| Specificity: | This antibody detects endogenous levels of OGDHL at Human |
| Immunogen: | Synthesized peptide derived from human C-ternal OGDHL |
| Function | 2-oxoglutarate dehydrogenase (E1-like) component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDHC) which mediates the decarboxylation of alpha-ketoglutarate in the tricarboxylic acid cycle. The OGDHC complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) while reducing NAD(+) to NADH. The OGDHC complex is mainly active in the mitochondrion. Involved in the inhibition of cell proliferation and in apoptosis. |
| Protein Name | 2-Oxoglutarate Dehydrogenase-Like - Mitochondrial2-Oxoglutarate Dehydrogenase Complex Component E1-LikeOgdc-E1-LikeAlpha-Ketoglutarate Dehydrogenase-Like |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-2-Oxoglutarate Dehydrogenase-Like - Mitochondrial antibodyAnti-2-Oxoglutarate Dehydrogenase Complex Component E1-Like antibodyAnti-Ogdc-E1-Like antibodyAnti-Alpha-Ketoglutarate Dehydrogenase-Like antibodyAnti-OGDHL antibodyAnti-KIAA1290 antibody |
Information sourced from Uniprot.org
