• Western blot analysis of extracts of U-937 cells, using ODC1 antibody (STJ11103541) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-ODC1 antibody (1-100) [S1MR] (STJ11103541)

SKU:
STJ11103541

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-ODC1 (1-100) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S1MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ODC1
Gene ID: 4953
Uniprot ID: DCOR_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ODC1 (P11926).
Immunogen Sequence: MNNFGNEEFDCHFLDEGFTA KDILDQKINEVSSSDDKDAF YVADLGDILKKHLRWLKALP RVTPFYAVKCNDSKAIVKTL AATGTGFDCASKTEIQLVQS
Post Translational Modifications S-Nitrosylation inhibits the enzyme. S-Nitrosylated in vitro on 4 cysteine residues.
Function Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
Protein Name Ornithine Decarboxylase
Odc
Database Links Reactome: R-HSA-350562
Reactome: R-HSA-351202
Alternative Antibody Names Anti-Ornithine Decarboxylase antibody
Anti-Odc antibody
Anti-ODC1 antibody

Information sourced from Uniprot.org

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