| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | OCIAD1 |
| Gene ID: | 54940 |
| Uniprot ID: | OCAD1_HUMAN |
| Immunogen Region: | 1-245 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human OCIAD1 (NP_060300.1). |
| Immunogen Sequence: | MNGRADFREPNAEVPRPIPH IGPDYIPTEEERRVFAECND ESFWFRSVPLAATSMLITQG LISKGILSSHPKYGSIPKLI LACIMGYFAGKLSYVKTCQE KFKKLENSPLGEALRSGQAR RSSPPGHYYQKSKYDSSVSG QSSFVTSPAADNIEMLPHYE PIPFSSSMNESAPTGITDHI VQGPDPNLEESPKRKNITYE ELRNKNRESYEVSLTQKTDP SVRPMHERVPKKEVKVNKY |
| Tissue Specificity | Isoform 1 is highly expressed in many tissues, including testis, brain, placenta, ovary, prostate and mammary gland. Isoform 2 expression is restricted to the central nervous system including brain, cerebellum and spinal cord. |
| Function | Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes. Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer. |
| Protein Name | Ocia Domain-Containing Protein 1Ovarian Cancer Immunoreactive Antigen Domain Containing 1Ovarian Carcinoma Immunoreactive Antigen |
| Cellular Localisation | Endosome |
| Alternative Antibody Names | Anti-Ocia Domain-Containing Protein 1 antibodyAnti-Ovarian Cancer Immunoreactive Antigen Domain Containing 1 antibodyAnti-Ovarian Carcinoma Immunoreactive Antigen antibodyAnti-OCIAD1 antibodyAnti-ASRIJ antibodyAnti-OCIA antibody |
Information sourced from Uniprot.org