Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-OCIAD1 (1-245) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
OCIAD1 |
Gene ID: |
54940 |
Uniprot ID: |
OCAD1_HUMAN |
Immunogen Region: |
1-245 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human OCIAD1 (NP_060300.1). |
Immunogen Sequence: |
MNGRADFREPNAEVPRPIPH IGPDYIPTEEERRVFAECND ESFWFRSVPLAATSMLITQG LISKGILSSHPKYGSIPKLI LACIMGYFAGKLSYVKTCQE KFKKLENSPLGEALRSGQAR RSSPPGHYYQKSKYDSSVSG QSSFVTSPAADNIEMLPHYE PIPFSSSMNESAPTGITDHI VQGPDPNLEESPKRKNITYE ELRNKNRESYEVSLTQKTDP SVRPMHERVPKKEVKVNKY |
Tissue Specificity | Isoform 1 is highly expressed in many tissues, including testis, brain, placenta, ovary, prostate and mammary gland. Isoform 2 expression is restricted to the central nervous system including brain, cerebellum and spinal cord. |
Function | Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes. Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer. |
Protein Name | Ocia Domain-Containing Protein 1Ovarian Cancer Immunoreactive Antigen Domain Containing 1Ovarian Carcinoma Immunoreactive Antigen |
Cellular Localisation | Endosome |
Alternative Antibody Names | Anti-Ocia Domain-Containing Protein 1 antibodyAnti-Ovarian Cancer Immunoreactive Antigen Domain Containing 1 antibodyAnti-Ovarian Carcinoma Immunoreactive Antigen antibodyAnti-OCIAD1 antibodyAnti-ASRIJ antibodyAnti-OCIA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance