| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NUP93 |
| Gene ID: | 9688 |
| Uniprot ID: | NUP93_HUMAN |
| Immunogen Region: | 670-819 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 670-819 of human NUP93 (NP_055484.3). |
| Immunogen Sequence: | IAERYRAQGISANKFVDSTF YLLLDLITFFDEYHSGHIDR AFDIIERLKLVPLNQESVEE RVAAFRNFSDEIRHNLSEVL LATMNILFTQFKRLKGTSPS SSSRPQRVIEDRDSQLRSQA RTLITFAGMIPYRTSGDTNA RLVQMEVLMN |
| Function | Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling. |
| Protein Name | Nuclear Pore Complex Protein Nup93 93 Kda Nucleoporin Nucleoporin Nup93 |
| Database Links | Reactome: R-HSA-1169408 Reactome: R-HSA-159227 Reactome: R-HSA-159230 Reactome: R-HSA-159231 Reactome: R-HSA-159236 Reactome: R-HSA-165054 Reactome: R-HSA-168271 Reactome: R-HSA-168276 Reactome: R-HSA-168325 Reactome: R-HSA-168333 Reactome: R-HSA-170822 Reactome: R-HSA-180746 Reactome: R-HSA-180910 Reactome: R-HSA-191859 Reactome: R-HSA-3108214 Reactome: R-HSA-3232142 Reactome: R-HSA-3301854 Reactome: R-HSA-3371453 Reactome: R-HSA-4085377 Reactome: R-HSA-4551638 Reactome: R-HSA-4570464 Reactome: R-HSA-4615885 Reactome: R-HSA-5578749 Reactome: R-HSA-5619107 Reactome: R-HSA-6784531 Reactome: R-HSA-9609690 Reactome: R-HSA-9610379 Reactome: R-HSA-9615933 Reactome: R-HSA-9705671 |
| Cellular Localisation | Nucleus Membrane Peripheral Membrane Protein Nucleus Nuclear Pore Complex Nucleus Envelope Localizes At The Nuclear Basket And At Or Near The Nuclear Entry To The Gated Channel Of The Pore |
| Alternative Antibody Names | Anti-Nuclear Pore Complex Protein Nup93 antibody Anti-93 Kda Nucleoporin antibody Anti-Nucleoporin Nup93 antibody Anti-NUP93 antibody Anti-KIAA0095 antibody |
Information sourced from Uniprot.org