Anti-NUCKS1 antibody (28-77) (STJ94572)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human NUCKS1. AA range:28-77
General Information
| Short Description | Rabbit polyclonal anti-Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 (28-77) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NUCKS1 |
| Gene ID | 64710 |
| Uniprot ID | NUCKS_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NUCKS1. AA range:28-77 |
| Immunogen Region | 28-77 |
| Specificity | NUCKS Polyclonal Antibody detects endogenous levels of NUCKS protein. |
Additional Info
| Tissue Specificity | Widely expressed, with highest levels in thyroid gland, prostate and uterus and in fetal liver, thymus and lung. |
| Post Translational Modifications | Phosphorylated in an ATM-dependent manner in response to DNA damage. Phosphorylated by CDK1 and casein kinase. |
| Function | Chromatin-associated protein involved in DNA repair by promoting homologous recombination (HR). Binds double-stranded DNA (dsDNA) and secondary DNA structures, such as D-loop structures, but with less affinity than RAD51AP1. |
| Protein Name | Nuclear Ubiquitous Casein And Cyclin-Dependent Kinase Substrate 1P1 |
| Database Links | |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Nuclear Ubiquitous Casein And Cyclin-Dependent Kinase Substrate 1 antibodyAnti-P1 antibodyAnti-NUCKS1 antibodyAnti-NUCKS antibodyAnti-JC7 antibody |
Information sourced from Uniprot.org