Anti-NTRK1/NTRK2/NTRK3 antibody (700-796) (STJ11101500)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NTRK1/NTRK2/NTRK3 (700-796) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:100-1:500IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NTRK2NTRK3491549164914NTRK2_HUMANNTRK3_HUMANNTRK1_HUMAN |
| Immunogen Region | 700-796 |
| Immunogen Sequence | LYRKFTTESDVWSFGVVLWE IFTYGKQPWYQLSNTEAIDC ITQGRELERPRACPPEVYAI MRGCWQREPQQRHSIKDVHA RLQALAQAPPVYLDVLG |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 700-796 of human NTRK1/NTRK2/NTRK3 (NP_002520.2). |
Additional Info
| Tissue Specificity | Q16620 - Isoform TrkB is expressed in the central and peripheral nervous system. In the central nervous system (CNS), expression is observed in the cerebral cortex, hippocampus, thalamus, choroid plexus, granular layer of the cerebellum, brain stem, and spinal cord. In the peripheral nervous system, it is expressed in many cranial ganglia, the ophthalmic nerve, the vestibular system, multiple facial structures, the submaxillary glands, and dorsal root ganglia. Isoform TrkB-T1 is mainly expressed in the brain but also detected in other tissues including pancreas, kidney and heart. Isoform TrkB-T-Shc is predominantly expressed in the brain.Q16288 - Widely expressed but mainly in nervous tissue. Isoform 2 is expressed at higher levels in adult brain than in fetal brain.P04629 - Isoform TrkA-I is found in most non-neuronal tissues. Isoform TrkA-II is primarily expressed in neuronal cells. TrkA-III is specifically expressed by pluripotent neural stem and neural crest progenitors.Q16620 - Isoform TrkB is expressed in the central and peripheral nervous system. In the central nervous system (CNS), expression is observed in the cerebral cortex, hippocampus, thalamus, choroid plexus, granular layer of the cerebellum, brain stem, and spinal cord. In the peripheral nervous system, it is expressed in many cranial ganglia, the ophthalmic nerve, the vestibular system, multiple facial structures, the submaxillary glands, and dorsal root ganglia. Isoform TrkB-T1 is mainly expressed in the brain but also detected in other tissues including pancreas, kidney and heart. Isoform TrkB-T-Shc is predominantly expressed in the brain.Q16288 - Widely expressed but mainly in nervous tissue. Isoform 2 is expressed at higher levels in adult brain than in fetal brain.P04629 - Isoform TrkA-I is found in most non-neuronal tissues. Isoform TrkA-II is primarily expressed in neuronal cells. TrkA-III is specifically expressed by pluripotent neural stem and neural crest progenitors. |
| Alternative Antibody Names | Anti-Bdnf/Nt-3 Growth Factors Receptor antibodyAnti-Gp145-Trkb antibodyAnti-Trk-B antibodyAnti-Neurotrophic Tyrosine Kinase Receptor Type 2 antibodyAnti-Trkb Tyrosine Kinase antibodyAnti-Tropomyosin-Related Kinase B antibodyAnti-NTRK2 antibodyAnti-TRKB antibodyAnti-Nt-3 Growth Factor Receptor antibodyAnti-Gp145-Trkc antibodyAnti-Trk-C antibodyAnti-Neurotrophic Tyrosine Kinase Receptor Type 3 antibodyAnti-Trkc Tyrosine Kinase antibodyAnti-NTRK3 antibodyAnti-TRKC antibodyAnti-High Affinity Nerve Growth Factor Receptor antibodyAnti-Neurotrophic Tyrosine Kinase Receptor Type 1 antibodyAnti-Trk1-Transforming Tyrosine Kinase Protein antibodyAnti-Tropomyosin-Related Kinase A antibodyAnti-Tyrosine Kinase Receptor antibodyAnti-Tyrosine Kinase Receptor A antibodyAnti-Trk-A antibodyAnti-Gp140trk antibodyAnti-P140-Trka antibodyAnti-NTRK1 antibodyAnti-MTC antibodyAnti-TRK antibodyAnti-TRKA antibodyAnti-Bdnf/Nt-3 Growth Factors Receptor antibodyAnti-Gp145-Trkb antibodyAnti-Trk-B antibodyAnti-Neurotrophic Tyrosine Kinase Receptor Type 2 antibodyAnti-Trkb Tyrosine Kinase antibodyAnti-Tropomyosin-Related Kinase B antibodyAnti-NTRK2 antibodyAnti-TRKB antibodyAnti-Nt-3 Growth Factor Receptor antibodyAnti-Gp145-Trkc antibodyAnti-Trk-C antibodyAnti-Neurotrophic Tyrosine Kinase Receptor Type 3 antibodyAnti-Trkc Tyrosine Kinase antibodyAnti-NTRK3 antibodyAnti-TRKC antibodyAnti-High Affinity Nerve Growth Factor Receptor antibodyAnti-Neurotrophic Tyrosine Kinase Receptor Type 1 antibodyAnti-Trk1-Transforming Tyrosine Kinase Protein antibodyAnti-Tropomyosin-Related Kinase A antibodyAnti-Tyrosine Kinase Receptor antibodyAnti-Tyrosine Kinase Receptor A antibodyAnti-Trk-A antibodyAnti-Gp140trk antibodyAnti-P140-Trka antibody |
Information sourced from Uniprot.org