| Short Description : | Rabbit polyclonal NSUN3 (1-120) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NSUN3 |
| Gene ID: | 63899 |
| Uniprot ID: | NSUN3_HUMAN |
| Immunogen Region: | 1-120 |
| Immunogen Sequence: | MLTQLKAKSEGKLAKQICKV VLDHFEKQYSKELGDAWNTV REILTSPSCWQYAVLLNRFN YPFELEKDLHLKGYHTLSQG SLPNYPKSVKCYLSRTPGRI PSERHQIGNLKKYYLLNAAS |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human NSUN3 (NP_071355.1). |
| Function | Mitochondrial tRNA methyltransferase that mediates methylation of cytosine to 5-methylcytosine (m5C) at position 34 of mt-tRNA(Met). mt-tRNA(Met) methylation at cytosine(34) takes place at the wobble position of the anticodon and initiates the formation of 5-formylcytosine (f(5)c) at this position. mt-tRNA(Met) containing the f(5)c modification at the wobble position enables recognition of the AUA codon in addition to the AUG codon, expanding codon recognition in mitochondrial translation. |
| Protein Name | TrnaCytosine(34-C(5-Methyltransferase - MitochondrialNol1/Nop2/Sun Domain Family Member 3 |
| Database Links | |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Trna antibodyAnti-Cytosine(34-C(5-Methyltransferase - Mitochondrial antibodyAnti-Nol1/Nop2/Sun Domain Family Member 3 antibodyAnti-NSUN3 antibodyAnti-MSTP077 antibodyAnti-UG0651E06 antibody |
Information sourced from Uniprot.org
