Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Rat/Human/Non-Human Primates |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-NSF (C-Term) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
Purification: |
This antibody was antigen affinity purified from pooled serum. |
Dilution Range: |
WB 1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
Nsf |
Gene ID: |
60355 |
Uniprot ID: |
NSF_RAT |
Immunogen Region: |
C-Term |
Immunogen: |
Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH. |
Tissue Specificity | Detected in brain (at protein level). |
Post Translational Modifications | Phosphorylation at Ser-569 interferes with homohexamerization. |
Function | Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling. |
Protein Name | Vesicle-Fusing AtpaseN-Ethylmaleimide-Sensitive Fusion ProteinNem-Sensitive Fusion ProteinVesicular-Fusion Protein Nsf |
Database Links | Reactome: R-RNO-204005Reactome: -RNO-416993Reactome: -RNO-6807878Reactome: -RNO-6811434Reactome: -RNO-6811438Reactome: -RNO-6811440 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Vesicle-Fusing Atpase antibodyAnti-N-Ethylmaleimide-Sensitive Fusion Protein antibodyAnti-Nem-Sensitive Fusion Protein antibodyAnti-Vesicular-Fusion Protein Nsf antibodyAnti-Nsf antibodyAnti-Erg1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance