Host: | Mouse |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-NSE is suitable for use in Immunohistochemistry research applications. |
Clonality : | Monoclonal |
Clone ID : | MRQ-55 |
Conjugation: | Unconjugated |
Isotype: | IgG2b |
Formulation: | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
Dilution Range: | IHC 1:50 – 1:200 |
Storage Instruction: | Store at 2-8°C upon receipt. |
Gene Symbol: | ENO2 |
Gene ID: | 2026 |
Uniprot ID: | ENOG_HUMAN |
Tissue Specificity | The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. |
Function | Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival. |
Protein Name | Gamma-Enolase 2-Phospho-D-Glycerate Hydro-Lyase Enolase 2 Neural Enolase Neuron-Specific Enolase Nse |
Database Links | Reactome: R-HSA-70171 Reactome: R-HSA-70263 |
Cellular Localisation | Cytoplasm Cell Membrane Can Translocate To The Plasma Membrane In Either The Homodimeric (Alpha/Alpha) Or Heterodimeric (Alpha/Gamma) Form |
Alternative Antibody Names | Anti-Gamma-Enolase antibody Anti-2-Phospho-D-Glycerate Hydro-Lyase antibody Anti-Enolase 2 antibody Anti-Neural Enolase antibody Anti-Neuron-Specific Enolase antibody Anti-Nse antibody Anti-ENO2 antibody |
Information sourced from Uniprot.org