| Tissue Specificity | Highly expressed in brain, heart and skeletal muscle. Expressed at lower level in liver and lung. |
| Function | Histone methyltransferase. Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K4me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression. |
| Protein Name | Histone-Lysine N-Methyltransferase Nsd3Nuclear Set Domain-Containing Protein 3Protein WhistleWhsc1-Like 1 Isoform 9 With Methyltransferase Activity To LysineWolf-Hirschhorn Syndrome Candidate 1-Like Protein 1Whsc1-Like Protein 1 |
| Database Links | Reactome: R-HSA-3214841 |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase Nsd3 antibodyAnti-Nuclear Set Domain-Containing Protein 3 antibodyAnti-Protein Whistle antibodyAnti-Whsc1-Like 1 Isoform 9 With Methyltransferase Activity To Lysine antibodyAnti-Wolf-Hirschhorn Syndrome Candidate 1-Like Protein 1 antibodyAnti-Whsc1-Like Protein 1 antibodyAnti-NSD3 antibodyAnti-WHSC1L1 antibodyAnti-DC28 antibody |
Information sourced from Uniprot.org
