| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Nuclear receptor subfamily 6 group A member 1 (70-150 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NR6A1 |
| Gene ID: | 2649 |
| Uniprot ID: | NR6A1_HUMAN |
| Immunogen Region: | 70-150 aa |
| Specificity: | NR6A1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 70-150 |
| Function | Orphan nuclear receptor that binds to a response element containing the sequence 5'-TCAAGGTCA-3'. Acts as a regulator of embryonic stem cell pluripotency by mediating repression of POU5F1/OCT4: binds to the DR0 element within the POU5F1/OCT4 promoter and inhibits POU5F1/OCT4 expression during embryonic stem cell differentiation. Involved in the regulation of gene expression in germ cell development during gametogenesis. |
| Protein Name | Nuclear Receptor Subfamily 6 Group A Member 1Germ Cell Nuclear FactorGcnfHgcnfRetinoid Receptor-Related Testis-Specific ReceptorRtrHrtr |
| Database Links | Reactome: R-HSA-2892247 Q15406-1Reactome: R-HSA-383280 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Nuclear Receptor Subfamily 6 Group A Member 1 antibodyAnti-Germ Cell Nuclear Factor antibodyAnti-Gcnf antibodyAnti-Hgcnf antibodyAnti-Retinoid Receptor-Related Testis-Specific Receptor antibodyAnti-Rtr antibodyAnti-Hrtr antibodyAnti-NR6A1 antibodyAnti-GCNF antibody |
Information sourced from Uniprot.org
