Anti-NPM3 antibody (30-140) (STJ11102921)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NPM3 (30-140) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NPM3 |
| Gene ID | 10360 |
| Uniprot ID | NPM3_HUMAN |
| Immunogen Region | 30-140 |
| Immunogen Sequence | APVTMDSFFFGCELSGHTRS FTFKVEEEDDAEHVLALTML CLTEGAKDECNVVEVVARNH DHQEIAVPVANLKLSCQPML SLDDFQLQPPVTFRLKSGSG PVRITGRHQIV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 30-140 of human NPM3 (NP_008924.1). |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Phosphorylated. |
| Function | Plays a role in the regulation of diverse cellular processes such as ribosome biogenesis, chromatin remodeling or protein chaperoning. Modulates the histone chaperone function and the RNA-binding activity of nucleolar phosphoprotein B23/NPM. Efficiently mediates chromatin remodeling when included in a pentamer containing NPM3 and NPM. |
| Protein Name | Nucleoplasmin-3 |
| Database Links | |
| Cellular Localisation | NucleusNucleolusMainly Found In The Granular Component Of The Nucleolus |
| Alternative Antibody Names | Anti-Nucleoplasmin-3 antibodyAnti-NPM3 antibody |
Information sourced from Uniprot.org