| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NPM3 (30-140) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NPM3 |
| Gene ID: |
10360 |
| Uniprot ID: |
NPM3_HUMAN |
| Immunogen Region: |
30-140 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 30-140 of human NPM3 (NP_008924.1). |
| Immunogen Sequence: |
APVTMDSFFFGCELSGHTRS FTFKVEEEDDAEHVLALTML CLTEGAKDECNVVEVVARNH DHQEIAVPVANLKLSCQPML SLDDFQLQPPVTFRLKSGSG PVRITGRHQIV |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Phosphorylated. |
| Function | Plays a role in the regulation of diverse cellular processes such as ribosome biogenesis, chromatin remodeling or protein chaperoning. Modulates the histone chaperone function and the RNA-binding activity of nucleolar phosphoprotein B23/NPM. Efficiently mediates chromatin remodeling when included in a pentamer containing NPM3 and NPM. |
| Protein Name | Nucleoplasmin-3 |
| Cellular Localisation | NucleusNucleolusMainly Found In The Granular Component Of The Nucleolus |
| Alternative Antibody Names | Anti-Nucleoplasmin-3 antibodyAnti-NPM3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
