Anti-NPHS2 antibody (300-388) (STJ119463)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NPHS2 (300-388) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NPHS2 |
| Gene ID | 7827 |
| Uniprot ID | PODO_HUMAN |
| Immunogen Region | 300-388 |
| Immunogen Sequence | AASESLRMAAEILSGTPAAV QLRYLHTLQSLSTEKPSTVV LPLPFDLLNCLSSPSNRTQG SLPFPSPSKPVEPLNPKKKD SPML |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 300-388 of human NPHS2 (NP_055440.1). |
Additional Info
| Tissue Specificity | Almost exclusively expressed in the podocytes of fetal and mature kidney glomeruli. |
| Post Translational Modifications | Isoform 2: Glycosylated. |
| Function | Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton. |
| Protein Name | Podocin |
| Database Links | Reactome: R-HSA-373753 |
| Cellular Localisation | Isoform 1: Cell MembranePeripheral Membrane ProteinIsoform 2: Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Podocin antibodyAnti-NPHS2 antibody |
Information sourced from Uniprot.org