| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NPB |
| Gene ID: | 256933 |
| Uniprot ID: | NPB_HUMAN |
| Immunogen Region: | 1-125 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human NPB (NP_683694.1). |
| Immunogen Sequence: | MARSATLAAAALALCLLLAP PGLAWYKPAAGHSSYSVGRA AGLLSGLRRSPYARRSQPYR GAEPPGGAGASPELQLHPRL RSLAVCVQDVAPNLQRCERL PDGRGTYQCKANVFLSLRAA DCLAA |
| Tissue Specificity | Widely expressed in the central nervous system. High levels are found in substantia nigra, hypothalamus, hippocampus, spinal cord, placenta and fetal brain.lower levels are found in testis, uterus and ovary. Also detected at high levels in colorectal adenocarcinoma. |
| Function | May be involved in the regulation of feeding, neuroendocrine system, memory, learning and in the afferent pain pathway. |
| Protein Name | Neuropeptide BPreproprotein L7Hppl7 Cleaved Into - Neuropeptide B-23Npb23Hl7 - Neuropeptide B-29Npb29Hl7c |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Neuropeptide B antibodyAnti-Preproprotein L7 antibodyAnti-Hppl7 Cleaved Into - Neuropeptide B-23 antibodyAnti-Npb23 antibodyAnti-Hl7 - Neuropeptide B-29 antibodyAnti-Npb29 antibodyAnti-Hl7c antibodyAnti-NPB antibodyAnti-PPL7 antibodyAnti-PPNPB antibody |
Information sourced from Uniprot.org