Anti-NOXO1 antibody (160-240 aa) (STJ191044)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 160-240
General Information
| Short Description | Rabbit polyclonal anti-NADPH oxidase organizer 1 (160-240 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NOXO1 |
| Gene ID | 124056 |
| Uniprot ID | NOXO1_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 160-240 |
| Immunogen Region | 160-240 aa |
| Specificity | NOXO1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Constitutively potentiates the superoxide-generating activity of NOX1 and NOX3 and is required for the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. Isoform 3 is more potent than isoform 1 in activating NOX3. Together with NOXA1, may also substitute to NCF1/p47phox and NCF2/p67phox in supporting the phagocyte NOX2/gp91phox superoxide-generating activity. |
| Protein Name | Nadph Oxidase Organizer 1Nadph Oxidase Regulatory ProteinNox Organizer 1Nox-Organizing Protein 1Sh3 And Px Domain-Containing Protein 5 |
| Database Links | Reactome: R-HSA-5668599Reactome: R-HSA-9013149Reactome: R-HSA-9013423Reactome: R-HSA-9673324 |
| Cellular Localisation | Isoform 3: Cell MembranePeripheral Membrane ProteinCytoplasmic SideIsoform 3 Associates With The Plasma Membrane In A Lipid-Dependent Manner |
| Alternative Antibody Names | Anti-Nadph Oxidase Organizer 1 antibodyAnti-Nadph Oxidase Regulatory Protein antibodyAnti-Nox Organizer 1 antibodyAnti-Nox-Organizing Protein 1 antibodyAnti-Sh3 And Px Domain-Containing Protein 5 antibodyAnti-NOXO1 antibodyAnti-P41NOX antibodyAnti-SH3PXD5 antibody |
Information sourced from Uniprot.org