• Western blot analysis of various lysates using NOXA1 Rabbit polyclonal antibody (STJ115784) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 30s.

Anti-NOXA1 antibody (140-300) (STJ115784)

SKU:
STJ115784

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-NOXA1 (140-300) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NOXA1
Gene ID: 10811
Uniprot ID: NOXA1_HUMAN
Immunogen Region: 140-300
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 140-300 of human NOXA1 (NP_006638.1).
Immunogen Sequence: EAASSLREAMSKWPEGSLNG LDSALDQVQRRGSLPPRQVP RGEVFRPHRWHLKHLEPVDF LGKAKVVASAIPDDQGWGVR PQQPQGPGANHDARSLIMDS PRAGTHQGPLDAETEVGADR CTSTAYQEQRPQVEQVGKQA PLSPGLPAMGGPGPGPCEDP A
Tissue Specificity Widely expressed. Detected in pancreas, liver, kidney, spleen, prostate, small intestine and colon.
Post Translational Modifications Interaction with YWHAZ depends on phosphorylation by PKA.
Function Functions as an activator of NOX1, a superoxide-producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3.
Protein Name Nadph Oxidase Activator 1
Nox Activator 1
Antigen Ny-Co-31
Ncf2-Like Protein
P67phox-Like Factor
P51-Nox
Database Links Reactome: R-HSA-5668599
Reactome: R-HSA-9013149
Reactome: R-HSA-9013423
Reactome: R-HSA-9673324
Cellular Localisation Cytoplasm
Cell Membrane
Translocation To Membranes Depends On Noxo1 Or Ncf1 And Maybe Rac1
Alternative Antibody Names Anti-Nadph Oxidase Activator 1 antibody
Anti-Nox Activator 1 antibody
Anti-Antigen Ny-Co-31 antibody
Anti-Ncf2-Like Protein antibody
Anti-P67phox-Like Factor antibody
Anti-P51-Nox antibody
Anti-NOXA1 antibody
Anti-P51NOX antibody

Information sourced from Uniprot.org

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