| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NOX1 |
| Gene ID: |
27035 |
| Uniprot ID: |
NOX1_HUMAN |
| Immunogen Region: |
415-564 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 415-564 of human NOX1 (NP_008983.2). |
| Immunogen Sequence: |
KSIWYKFQCADHNLKTKKIY FYWICRETGAFSWFNNLLTS LEQEMEELGKVGFLNYRLFL TGWDSNIVGHAALNFDKATD IVTGLKQKTSFGRPMWDNEF STIATSHPKSVVGVFLCGPR TLAKSLRKCCHRYSSLDPRK VQFYFNKENF |
| Tissue Specificity | Isoform NOH-1L: Detected in colon, uterus, prostate, and colon carcinoma, but not in peripheral blood leukocytes. |
| Post Translational Modifications | Phosphorylation at Thr-430 mediated by PKC/PRKBC positively regulates its interaction with NOXA1 and enzyme activity. |
| Function | NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor. Isoform NOH-1L: NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor. |
| Protein Name | Nadph Oxidase 1Nox-1Mitogenic Oxidase 1Mox-1Nadh/Nadph Mitogenic Oxidase Subunit P65-MoxNoh-1 |
| Database Links | Reactome: R-HSA-5668599Reactome: R-HSA-9013149Reactome: R-HSA-9013423Reactome: R-HSA-9673324 |
| Cellular Localisation | Cell ProjectionInvadopodium MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Nadph Oxidase 1 antibodyAnti-Nox-1 antibodyAnti-Mitogenic Oxidase 1 antibodyAnti-Mox-1 antibodyAnti-Nadh/Nadph Mitogenic Oxidase Subunit P65-Mox antibodyAnti-Noh-1 antibodyAnti-NOX1 antibodyAnti-MOX1 antibodyAnti-NOH1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
