• Western blot analysis of various lysates using NOP10 Rabbit polyclonal antibody (STJ11100207) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3min.

Anti-NOP10 antibody (1-64) (STJ11100207)

SKU:
STJ11100207

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-NOP10 (1-64) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NOP10
Gene ID: 55505
Uniprot ID: NOP10_HUMAN
Immunogen Region: 1-64
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-64 of human NOP10 (NP_061118.1).
Immunogen Sequence: MFLQYYLNEQGDRVYTLKKF DPMGQQTCSAHPARFSPDDK YSRHRITIKKRFKVLMTQQP RPVL
Function Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
Protein Name H/Aca Ribonucleoprotein Complex Subunit 3
Nucleolar Protein 10
Nucleolar Protein Family A Member 3
Snornp Protein Nop10
Database Links Reactome: R-HSA-171319
Reactome: R-HSA-6790901
Cellular Localisation Nucleus
Nucleolus
Cajal Body
Also Localized To Cajal Bodies (Coiled Bodies)
Alternative Antibody Names Anti-H/Aca Ribonucleoprotein Complex Subunit 3 antibody
Anti-Nucleolar Protein 10 antibody
Anti-Nucleolar Protein Family A Member 3 antibody
Anti-Snornp Protein Nop10 antibody
Anti-NOP10 antibody
Anti-NOLA3 antibody

Information sourced from Uniprot.org

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