| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NLRP7 |
| Gene ID: | 199713 |
| Uniprot ID: | NALP7_HUMAN |
| Immunogen Region: | 800-1000 |
| Immunogen Sequence: | CRLTEASCKDLAAVLVVSKK LTHLCLAKNPIGDTGVKFLC EGLSYPDCKLQTLVLQQCSI TKLGCRYLSEALQEACSLTN LDLSINQIARGLWILCQALE NPNCNLKHLRLWSCSLMPFY CQHLGSALLSNQKLETLDLG QNHLWKSGIIKLFGVLRQRT GSLKILRLKTYETNLEIKKL LEEVKEKNPKLTIDCNASGA T |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 800-1000 of human NLRP7 (NP_631915.2). |
| Tissue Specificity | Expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. Not detected in skeletal muscle. |
| Function | Inhibits CASP1/caspase-1-dependent IL1B secretion. |
| Protein Name | Nacht - Lrr And Pyd Domains-Containing Protein 7Nucleotide-Binding Oligomerization Domain Protein 12Pyrin-Containing Apaf1-Like Protein 3 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Nacht - Lrr And Pyd Domains-Containing Protein 7 antibodyAnti-Nucleotide-Binding Oligomerization Domain Protein 12 antibodyAnti-Pyrin-Containing Apaf1-Like Protein 3 antibodyAnti-NLRP7 antibodyAnti-NALP7 antibodyAnti-NOD12 antibodyAnti-PYPAF3 antibody |
Information sourced from Uniprot.org
