Anti-NLRP7 antibody (800-1000) (STJ113232)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NLRP7 (800-1000) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NLRP7 |
| Gene ID | 199713 |
| Uniprot ID | NALP7_HUMAN |
| Immunogen Region | 800-1000 |
| Immunogen Sequence | CRLTEASCKDLAAVLVVSKK LTHLCLAKNPIGDTGVKFLC EGLSYPDCKLQTLVLQQCSI TKLGCRYLSEALQEACSLTN LDLSINQIARGLWILCQALE NPNCNLKHLRLWSCSLMPFY CQHLGSALLSNQKLETLDLG QNHLWKSGIIKLFGVLRQRT GSLKILRLKTYETNLEIKKL LEEVKEKNPKLTIDCNASGA T |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 800-1000 of human NLRP7 (NP_631915.2). |
Additional Info
| Tissue Specificity | Expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. Not detected in skeletal muscle. |
| Function | Inhibits CASP1/caspase-1-dependent IL1B secretion. |
| Protein Name | Nacht - Lrr And Pyd Domains-Containing Protein 7Nucleotide-Binding Oligomerization Domain Protein 12Pyrin-Containing Apaf1-Like Protein 3 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Nacht - Lrr And Pyd Domains-Containing Protein 7 antibodyAnti-Nucleotide-Binding Oligomerization Domain Protein 12 antibodyAnti-Pyrin-Containing Apaf1-Like Protein 3 antibodyAnti-NLRP7 antibodyAnti-NALP7 antibodyAnti-NOD12 antibodyAnti-PYPAF3 antibody |
Information sourced from Uniprot.org