• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using NKX3.1 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Nkx-3.1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-NKX3-1 antibody (1-50) (STJ94507)

SKU:
STJ94507

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Homeobox protein Nkx-3.1 (1-50) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NKX3-1
Gene ID: 4824
Uniprot ID: NKX31_HUMAN
Immunogen Region: 1-50
Specificity: Nkx-3.1 Polyclonal Antibody detects endogenous levels of Nkx-3.1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human NKX3-1. AA range:1-50
Tissue Specificity Highly expressed in the prostate and, at a lower level, in the testis.
Post Translational Modifications Ubiquitinated by TOPORS.monoubiquitinated at several residues and also polyubiquitinated on single residues.
Function Transcription factor, which binds preferentially the consensus sequence 5'-TAAGTAG-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
Protein Name Homeobox Protein Nkx-3.1
Homeobox Protein Nk-3 Homolog A
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Homeobox Protein Nkx-3.1 antibody
Anti-Homeobox Protein Nk-3 Homolog A antibody
Anti-NKX3-1 antibody
Anti-NKX3.1 antibody
Anti-NKX3A antibody

Information sourced from Uniprot.org

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