• Western blot analysis of extracts of various cell lines, using NKX3. 1 Rabbit monoclonal antibody (STJ11103100) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-NKX3.1 antibody (1-234) [S0MR] (STJ11103100)

SKU:
STJ11103100

£146.50 - £639.50
Shipping:
Free Shipping
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-NKX3.1 (1-234) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S0MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NKX3-1
Gene ID: 4824
Uniprot ID: NKX31_HUMAN
Immunogen Region: 1-234
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-234 of human NKX3.1 (Q99801).
Immunogen Sequence: MLRVPEPRPGEAKAEGAAPP TPSKPLTSFLIQDILRDGAQ RQGGRTSSQRQRDPEPEPEP EPEGGRSRAGAQNDQLSTGP RAAPEEAETLAETEPERHLG SYLLDSENTSGALPRLPQTP KQPQKRSRAAFSHTQVIELE RKFSHQKYLSAPERAHLAKN LKLTETQVKIWFQNRRYKTK RKQLSSELGDLEKHSSLPAL KEEAFSRASLVSVYNSYPYY PYLYCVGSWSPAFW
Tissue Specificity Highly expressed in the prostate and, at a lower level, in the testis.
Post Translational Modifications Ubiquitinated by TOPORS.monoubiquitinated at several residues and also polyubiquitinated on single residues.
Function Transcription factor, which binds preferentially the consensus sequence 5'-TAAGTAG-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
Protein Name Homeobox Protein Nkx-3.1
Homeobox Protein Nk-3 Homolog A
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Homeobox Protein Nkx-3.1 antibody
Anti-Homeobox Protein Nk-3 Homolog A antibody
Anti-NKX3-1 antibody
Anti-NKX3.1 antibody
Anti-NKX3A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance