| Host: | Mouse |
| Applications: | IF/ICC/IHC/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-Neuronal nuclei antigen/RNA binding protein fox-1 homolog 3 (N-Term) for use in IF, ICC, IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | 1B7 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b, kappa |
| Formulation: | Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide |
| Purification: | IgG |
| Dilution Range: | WB 0.73611111111111116IHC 1:1000-1:2000ICC 1:1000-1:2000 |
| Storage Instruction: | Spin vial briefly before opening. Reconstitute with 100 µL sterile-filtered, ultrapure water to achieve a 1 mg/mL concentration. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8°C After reconstitution of lyophilized anti |
| Gene Symbol: | RBFOX3 |
| Gene ID: | 146713 |
| Uniprot ID: | RFOX3_HUMAN |
| Immunogen Region: | N-Term |
| Specificity: | Species cross-reactivity includes human, rat, and mouse. |
| Immunogen: | The antibody has been made against a recombinant construct, based on the N-terminal (100 amino acids) of human FOX3 expressed in and purified from E Coli. |
| Immunogen Sequence: | Human |
| Function | Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD). |
| Protein Name | Rna Binding Protein Fox-1 Homolog 3Fox-1 Homolog CNeuronal Nuclei AntigenNeun Antigen |
| Database Links | Reactome: R-HSA-9768919 |
| Cellular Localisation | NucleusCytoplasmLargely Restricted To Neuronal NucleiHoweverSignificant Cytoplasmic Localization In Neurons From Brains From Hiv-Infected Individuals With Cognitive Impairment |
| Alternative Antibody Names | Anti-Rna Binding Protein Fox-1 Homolog 3 antibodyAnti-Fox-1 Homolog C antibodyAnti-Neuronal Nuclei Antigen antibodyAnti-Neun Antigen antibodyAnti-RBFOX3 antibody |
Information sourced from Uniprot.org
