Anti-Neuronal nuclei antigen/RNA binding protein fox-1 homolog 3 antibody (N-Term) [1B7] (STJA0040826)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2b, kappa
ImmunogenThe antibody has been made against a recombinant construct, based on the N-terminal (100 amino acids) of human FOX3 expressed in and purified from E Coli.
General Information
| Short Description | Mouse monoclonal anti-Neuronal nuclei antigen/RNA binding protein fox-1 homolog 3 (N-Term) for use in IF, ICC, IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/ICC/IHC/WB |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 1B7 |
| Isotype | IgG2b, kappa |
| Conjugation | Unconjugated |
| Purification | IgG |
| Dilution Range | WB 0.73611111111111116IHC 1:1000-1:2000ICC 1:1000-1:2000 |
| Formulation | Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide |
| Storage Instruction | Spin vial briefly before opening. Reconstitute with 100 µL sterile-filtered, ultrapure water to achieve a 1 mg/mL concentration. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8°C After reconstitution of lyophilized anti |
Target Information
| Gene Symbol | RBFOX3 |
| Gene ID | 146713 |
| Uniprot ID | RFOX3_HUMAN |
| Immunogen | The antibody has been made against a recombinant construct, based on the N-terminal (100 amino acids) of human FOX3 expressed in and purified from E Coli. |
| Immunogen Region | N-Term |
| Immunogen Sequence | Human |
| Specificity | Species cross-reactivity includes human, rat, and mouse. |
Additional Info
| Function | Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD). |
| Protein Name | Rna Binding Protein Fox-1 Homolog 3Fox-1 Homolog CNeuronal Nuclei AntigenNeun Antigen |
| Database Links | Reactome: R-HSA-9768919 |
| Cellular Localisation | NucleusCytoplasmLargely Restricted To Neuronal NucleiHoweverSignificant Cytoplasmic Localization In Neurons From Brains From Hiv-Infected Individuals With Cognitive Impairment |
| Alternative Antibody Names | Anti-Rna Binding Protein Fox-1 Homolog 3 antibodyAnti-Fox-1 Homolog C antibodyAnti-Neuronal Nuclei Antigen antibodyAnti-Neun Antigen antibodyAnti-RBFOX3 antibody |
Information sourced from Uniprot.org