Anti-NEO1 antibody (82-132 aa) (STJ195573)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human NEO1 at the amino acid range 82-132
General Information
| Short Description | Rabbit polyclonal anti-Neogenin (82-132 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NEO1 |
| Gene ID | 4756 |
| Uniprot ID | NEO1_HUMAN |
| Immunogen | Synthesized peptide derived from the human NEO1 at the amino acid range 82-132 |
| Immunogen Region | 82-132 aa |
| Specificity | This antibody detects endogenous levels of NEO1 at Human/Mouse/Rat |
Additional Info
| Function | Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response. |
| Protein Name | NeogeninImmunoglobulin Superfamily Dcc Subclass Member 2 |
| Database Links | Reactome: R-HSA-373752Reactome: R-HSA-525793 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Neogenin antibodyAnti-Immunoglobulin Superfamily Dcc Subclass Member 2 antibodyAnti-NEO1 antibodyAnti-IGDCC2 antibodyAnti-NGN antibody |
Information sourced from Uniprot.org