| Tissue Specificity | Poorly expressed in cerebellum, trachea, lung, appendix, and uterus. |
| Post Translational Modifications | Phosphorylated by NEK2. Phosphorylation at Ser-273 is important for its activation. |
| Function | Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation. |
| Protein Name | Serine/Threonine-Protein Kinase Nek11Never In Mitosis A-Related Kinase 11Nima-Related Protein Kinase 11 |
| Cellular Localisation | NucleusNucleolusNuclear During Interphase But Moves To The Polar Microtubules During Prometaphase And MetaphaseAccumulates In The Nucleolus In G1/S-Arrested Cells |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase Nek11 antibodyAnti-Never In Mitosis A-Related Kinase 11 antibodyAnti-Nima-Related Protein Kinase 11 antibodyAnti-NEK11 antibody |
Information sourced from Uniprot.org
