| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PVRL1 (450-517) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NECTIN1 |
| Gene ID: |
5818 |
| Uniprot ID: |
NECT1_HUMAN |
| Immunogen Region: |
450-517 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 450-517 of human PVRL1 (NP_002846.3). |
| Immunogen Sequence: |
ERKVGGPHPKYDEDAKRPYF TVDEAEARQDGYGDRTLGYQ YDPEQLDLAENMVSQNDGSF ISKKEWYV |
| Function | Promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between NECTIN1 and NECTIN3 and between NECTIN1 and NECTIN4. Has some neurite outgrowth-promoting activity. (Microbial infection) Acts as a receptor for herpes simplex virus 1/HHV-1, herpes simplex virus 2/HHV-2, and pseudorabies virus/PRV. |
| Protein Name | Nectin-1Herpes Virus Entry Mediator CHerpesvirus Entry Mediator CHvecHerpesvirus Ig-Like ReceptorHigrNectin Cell Adhesion Molecule 1Poliovirus Receptor-Related Protein 1Cd Antigen Cd111 |
| Database Links | Reactome: R-HSA-418990Reactome: R-HSA-420597 |
| Cellular Localisation | Isoform Alpha: Cell MembraneSingle-Pass Type I Membrane ProteinPresynaptic Cell MembraneIsoform Delta: Cell MembraneIsoform Gamma: Secreted |
| Alternative Antibody Names | Anti-Nectin-1 antibodyAnti-Herpes Virus Entry Mediator C antibodyAnti-Herpesvirus Entry Mediator C antibodyAnti-Hvec antibodyAnti-Herpesvirus Ig-Like Receptor antibodyAnti-Higr antibodyAnti-Nectin Cell Adhesion Molecule 1 antibodyAnti-Poliovirus Receptor-Related Protein 1 antibodyAnti-Cd Antigen Cd111 antibodyAnti-NECTIN1 antibodyAnti-HVEC antibodyAnti-PRR1 antibodyAnti-PVRL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
