Anti-Nectin 2 antibody (STJA0038010)

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STJA0038010
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Host: Rabbit
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Nectin 2 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Purification: Affinity Purified
Dilution Range: IHC 1:100-1:200
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: NECTIN2
Gene ID: 5819
Uniprot ID: NECT2_HUMAN
Immunogen: Recombinant protein of human Nectin 2
Tissue Specificity Ubiquitous.
Function Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein. (Microbial infection) Acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV).
Protein Name Nectin-2
Herpes Virus Entry Mediator B
Herpesvirus Entry Mediator B
Hveb
Nectin Cell Adhesion Molecule 2
Poliovirus Receptor-Related Protein 2
Cd Antigen Cd112
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-418990
Reactome: R-HSA-420597
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Nectin-2 antibody
Anti-Herpes Virus Entry Mediator B antibody
Anti-Herpesvirus Entry Mediator B antibody
Anti-Hveb antibody
Anti-Nectin Cell Adhesion Molecule 2 antibody
Anti-Poliovirus Receptor-Related Protein 2 antibody
Anti-Cd Antigen Cd112 antibody
Anti-NECTIN2 antibody
Anti-HVEB antibody
Anti-PRR2 antibody
Anti-PVRL2 antibody

Information sourced from Uniprot.org

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