| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NDC1 |
| Gene ID: | 55706 |
| Uniprot ID: | NDC1_HUMAN |
| Immunogen Region: | 340-530 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 340-530 of human NDC1 (NP_060557.3). |
| Immunogen Sequence: | QYSPSRRQEVFSLSQPGGHP HNWTAISRECLNLLNGMTQK LILYQEAAATNGRVSSSYPV EPKKLNSPEETAFQTPKSSQ MPRPSVPPLVKTSLFSSKLS TPDVVSPFGTPFGSSVMNRM AGIFDVNTCYGSPQSPQLIR RGPRLWTSASDQQMTEFSNP SPSTSISAEGKTMRQPSVIY SWIQNKREQIK |
| Function | Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane. |
| Protein Name | Nucleoporin Ndc1Hndc1Transmembrane Protein 48 |
| Database Links | Reactome: R-HSA-1169408Reactome: R-HSA-159227Reactome: R-HSA-159230Reactome: R-HSA-159231Reactome: R-HSA-159236Reactome: R-HSA-165054Reactome: R-HSA-168271Reactome: R-HSA-168276Reactome: R-HSA-168325Reactome: R-HSA-168333Reactome: R-HSA-170822Reactome: R-HSA-180746Reactome: R-HSA-180910Reactome: R-HSA-191859Reactome: R-HSA-3108214Reactome: R-HSA-3232142Reactome: R-HSA-3301854Reactome: R-HSA-3371453Reactome: R-HSA-4085377Reactome: R-HSA-4551638Reactome: R-HSA-4570464Reactome: R-HSA-4615885Reactome: R-HSA-5578749Reactome: R-HSA-5619107Reactome: R-HSA-6784531Reactome: R-HSA-9609690Reactome: R-HSA-9610379Reactome: R-HSA-9615933Reactome: R-HSA-9705671 |
| Cellular Localisation | NucleusNuclear Pore ComplexNucleus MembraneMulti-Pass Membrane ProteinCentral Core Structure Of The Nuclear Pore Complex |
| Alternative Antibody Names | Anti-Nucleoporin Ndc1 antibodyAnti-Hndc1 antibodyAnti-Transmembrane Protein 48 antibodyAnti-NDC1 antibodyAnti-TMEM48 antibody |
Information sourced from Uniprot.org
