Anti-NCS1 antibody (1-190aa) [AT11B8] (STJA0041816)

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STJA0041816
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Short Description :Mouse monoclonal anti-NCS1 (1-190aa) for use in ELISA, WB and FACS in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:ELISA/WB/FACS
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :AT11B8
Isotype:IgG1k
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:By protein-A affinity chromatography
Formulation:Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:NCS1
Gene ID:23413
Uniprot ID:NCS1_HUMAN
Accession Number:NP_055101
Immunogen:Recombinant human NCS1 (1-190aa) purified from E. coli
Immunogen Region:1-190aa
Function Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin. Stimulates PI4KB kinase activity. Involved in long-term synaptic plasticity through its interaction with PICK1. May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel.
Protein Name Neuronal Calcium Sensor 1
Ncs-1
Frequenin Homolog
Frequenin-Like Protein
Frequenin-Like Ubiquitous Protein
Database Links
Cellular Localisation Golgi Apparatus
Postsynaptic Density
Cytoplasm
Perinuclear Region
Cell Membrane
Peripheral Membrane Protein
Membrane
Lipid-Anchor
Associated With Golgi Stacks
Post-Synaptic Densities Of Dendrites
And In The Pre-Synaptic Nerve Terminal At Neuromuscular Junctions
Alternative Antibody Names Anti-Neuronal Calcium Sensor 1 antibody
Anti-Ncs-1 antibody
Anti-Frequenin Homolog antibody
Anti-Frequenin-Like Protein antibody
Anti-Frequenin-Like Ubiquitous Protein antibody
Anti-NCS1 antibody
Anti-FLUP antibody
Anti-FREQ antibody

Information sourced from Uniprot.org