| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NCR2 |
| Gene ID: | 9436 |
| Uniprot ID: | NCTR2_HUMAN |
| Immunogen Region: | 22-192 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-192 of human NCR2 (NP_004819.2). |
| Immunogen Sequence: | QSKAQVLQSVAGQTLTVRCQ YPPTGSLYEKKGWCKEASAL VCIRLVTSSKPRTMAWTSRF TIWDDPDAGFFTVTMTDLRE EDSGHYWCRIYRPSDNSVSK SVRFYLVVSPASASTQTSWT PRDLVSSQTQTQSCVPPTAG ARQAPESPSTIPVPSQPQNS TLRPGPAAPIA |
| Tissue Specificity | Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells. |
| Function | Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. |
| Protein Name | Natural Cytotoxicity Triggering Receptor 2Lymphocyte Antigen 95 HomologNk Cell-Activating ReceptorNatural Killer Cell P44-Related ProteinNk-P44Nkp44Cd Antigen Cd336 |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-2172127 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Natural Cytotoxicity Triggering Receptor 2 antibodyAnti-Lymphocyte Antigen 95 Homolog antibodyAnti-Nk Cell-Activating Receptor antibodyAnti-Natural Killer Cell P44-Related Protein antibodyAnti-Nk-P44 antibodyAnti-Nkp44 antibodyAnti-Cd Antigen Cd336 antibodyAnti-NCR2 antibodyAnti-LY95 antibody |
Information sourced from Uniprot.org