| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-NCF1 (291-390) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S2MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NCF1 |
| Gene ID: |
653361 |
| Uniprot ID: |
NCF1_HUMAN |
| Immunogen Region: |
291-390 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 291-390 of human p47phox/NCF1 (P14598). |
| Immunogen Sequence: |
QRQIKRGAPPRRSSIRNAHS IHQRSRKRLSQDAYRRNSVR FLQQRRRQARPGPQSPGSPL EEERQTQRSKPQPAVPPRPS ADLILNRCSESTKRKLASAV |
| Tissue Specificity | Detected in peripheral blood monocytes and neutrophils (at protein level). |
| Post Translational Modifications | Phosphorylated by PRKCD.phosphorylation induces activation of NCF1 and NADPH oxidase activity. |
| Function | NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). |
| Protein Name | Neutrophil Cytosol Factor 1Ncf-147 Kda Autosomal Chronic Granulomatous Disease Protein47 Kda Neutrophil Oxidase FactorNcf-47kNeutrophil Nadph Oxidase Factor 1Nox Organizer 2Nox-Organizing Protein 2Sh3 And Px Domain-Containing Protein 1aP47-Phox |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-1236973Reactome: R-HSA-3299685Reactome: R-HSA-4420097Reactome: R-HSA-5668599Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013423 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Neutrophil Cytosol Factor 1 antibodyAnti-Ncf-1 antibodyAnti-47 Kda Autosomal Chronic Granulomatous Disease Protein antibodyAnti-47 Kda Neutrophil Oxidase Factor antibodyAnti-Ncf-47k antibodyAnti-Neutrophil Nadph Oxidase Factor 1 antibodyAnti-Nox Organizer 2 antibodyAnti-Nox-Organizing Protein 2 antibodyAnti-Sh3 And Px Domain-Containing Protein 1a antibodyAnti-P47-Phox antibodyAnti-NCF1 antibodyAnti-NOXO2 antibodyAnti-SH3PXD1A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
