Anti-NCAM1 antibody (STJA0037793)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human NCAM1
General Information
| Short Description | Rabbit monoclonal anti-NCAM1 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | IHC-P-1:1000-1:2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | NCAM1 |
| Gene ID | 4684 |
| Uniprot ID | NCAM1_HUMAN |
| Immunogen | A synthesized peptide derived from human NCAM1 |
Additional Info
| Post Translational Modifications | Polysialylated at Asn-459 and Asn-488 by ST8SIA2 and ST8SIA4. Polysialylation modulates cell interactions by confering both attractive and repulsive properties that are highly regulated by ST8SIA2 and ST8SIA4. Polysialylation is formed on a-2,3-linked sialic acid of core glycans. |
| Function | This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. (Microbial infection) Acts as a receptor for rabies virus. (Microbial infection) Acts as a receptor for Zika virus. |
| Protein Name | Neural Cell Adhesion Molecule 1N-Cam-1Ncam-1Cd Antigen Cd56 |
| Database Links | Reactome: R-HSA-3000178Reactome: R-HSA-375165Reactome: R-HSA-419037Reactome: R-HSA-445144Reactome: R-HSA-5673001Reactome: R-HSA-877300 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Cell MembraneIsoform 3: Cell MembraneLipid-AnchorGpi-AnchorIsoform 4: Cell MembraneIsoform 5: SecretedIsoform 6: Secreted |
| Alternative Antibody Names | Anti-Neural Cell Adhesion Molecule 1 antibodyAnti-N-Cam-1 antibodyAnti-Ncam-1 antibodyAnti-Cd Antigen Cd56 antibodyAnti-NCAM1 antibodyAnti-NCAM antibody |
Information sourced from Uniprot.org