| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NBAS (1-70) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NBAS |
| Gene ID: |
51594 |
| Uniprot ID: |
NBAS_HUMAN |
| Immunogen Region: |
1-70 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human NBAS (NP_056993.2). |
| Immunogen Sequence: |
MAAPESGPALSPGTAEGEEE TILYDLLVNTEWPPETEVQP RGNQKHGASFIITKAIRDRL LFLRQYIWYS |
| Tissue Specificity | Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small intestine and thymus. Well expressed in retinal ganglion cells, epidermal skin cells, and leukocytes. Up-regulated together with N-myc in some neuroblastoma cell lines. |
| Function | Involved in Golgi-to-endoplasmic reticulum (ER) retrograde transport.the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER. Required for normal embryonic development. May play a role in the nonsense-mediated decay pathway of mRNAs containing premature stop codons. |
| Protein Name | Nbas Subunit Of Nrz Tethering ComplexNeuroblastoma-Amplified Gene ProteinNeuroblastoma-Amplified Sequence |
| Database Links | Reactome: R-HSA-6811434 |
| Cellular Localisation | CytoplasmEndoplasmic ReticulumEndoplasmic Reticulum MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Nbas Subunit Of Nrz Tethering Complex antibodyAnti-Neuroblastoma-Amplified Gene Protein antibodyAnti-Neuroblastoma-Amplified Sequence antibodyAnti-NBAS antibodyAnti-NAG antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
