Immunofluorescence analysis of H9C2 cells using NBAS Rabbit polyclonal antibody (STJ24688) at dilution of 1:100. Blue: DAPI for nuclear staining.

Anti-NBAS antibody (1-70) (STJ24688)

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STJ24688
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:200-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NBAS
Gene ID: 51594
Uniprot ID: NBAS_HUMAN
Immunogen Region: 1-70
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human NBAS (NP_056993.2).
Immunogen Sequence: MAAPESGPALSPGTAEGEEE TILYDLLVNTEWPPETEVQP RGNQKHGASFIITKAIRDRL LFLRQYIWYS
Tissue Specificity Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small intestine and thymus. Well expressed in retinal ganglion cells, epidermal skin cells, and leukocytes. Up-regulated together with N-myc in some neuroblastoma cell lines.
Function Involved in Golgi-to-endoplasmic reticulum (ER) retrograde transport.the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER. Required for normal embryonic development. May play a role in the nonsense-mediated decay pathway of mRNAs containing premature stop codons.
Protein Name Nbas Subunit Of Nrz Tethering Complex
Neuroblastoma-Amplified Gene Protein
Neuroblastoma-Amplified Sequence
Database Links Reactome: R-HSA-6811434
Cellular Localisation Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Peripheral Membrane Protein
Alternative Antibody Names Anti-Nbas Subunit Of Nrz Tethering Complex antibody
Anti-Neuroblastoma-Amplified Gene Protein antibody
Anti-Neuroblastoma-Amplified Sequence antibody
Anti-NBAS antibody
Anti-NAG antibody

Information sourced from Uniprot.org

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