Host: |
Mouse |
Applications: |
IHC-F/IF/IP/IHC-P/WB |
Reactivity: |
Human/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-N-Cadherin is suitable for use in Immunohistochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry and Western Blot research applications. |
Clonality: |
Monoclonal |
Clone ID: |
13A9 |
Conjugation: |
Unconjugated |
Isotype: |
IgG1 |
Formulation: |
PBS with <0.1% sodium azide |
Purification: |
Purified |
Concentration: |
1 mg/mL |
Storage Instruction: |
Store aliquots at-20°C, and thawed aliquots at 2-8°C. |
Immunogen: |
Recombinant MBP fusion protein containing the entire cytoplasmic domain of human N-cadherin |
Background | Mouse anti Human N-cadherin antibody, clone 13A9 recognizes neural cadherin, otherwise known as CD325, a calcium dependent cell-cell adhesion glycoprotein, and member of the cadherin superfamily, which links to the actin cytoskeleton via catenins, and plays a role in cell-matrix adhesion, cell growth and differentiation, and the establishment of left-right asymmetry. Mouse anti Human N-cadherin antibody, clone 13A9 does not recognize E-cadherin, M-cadherin or P-cadherin (Knudsen et al. 1995). Mouse anti Human N-cadherin antibody, clone 13A9 is a reliable marker for the differential diagnosis of pleural mesotheliomas and lung adenocarcinomas, when used in conjunction with E-cadherin (Han et al. 1997). |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance