Anti-MYT1 antibody (650-820) (STJ112720)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MYT1 (650-820) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYT1 |
| Gene ID | 4661 |
| Uniprot ID | MYT1_HUMAN |
| Immunogen Region | 650-820 |
| Immunogen Sequence | KPQDLPSKSVDIEVDENGTL DLSMHKHRKRENAFPSSSSC SSSPGVKSPDASQRHSSTSA PSSSMTSPQSSQASRQDEWD RPLDYTKPSRLREEEPEESE PAAHSFASSEADDQEVSEEN FEERKYPGEVTLTNFKLKFL SKDIKKELLTCPTPGCDGSG HITGNYASHRS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 650-820 of human MYT1 (NP_004526.1). |
Additional Info
| Tissue Specificity | Mostly in developing nervous system. Expressed in neural progenitors and oligodendrocyte lineage cells. More highly expressed in oligodendrocyte progenitors than in differentiated oligodendrocytes. |
| Function | Binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription. |
| Protein Name | Myelin Transcription Factor 1Myt1Myelin Transcription Factor IMytiPlpb1Proteolipid Protein-Binding Protein |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Myelin Transcription Factor 1 antibodyAnti-Myt1 antibodyAnti-Myelin Transcription Factor I antibodyAnti-Myti antibodyAnti-Plpb1 antibodyAnti-Proteolipid Protein-Binding Protein antibodyAnti-MYT1 antibodyAnti-KIAA0835 antibodyAnti-KIAA1050 antibodyAnti-MTF1 antibodyAnti-MYTI antibodyAnti-PLPB1 antibody |
Information sourced from Uniprot.org