Anti-MYRIP antibody (591-641) (STJA0006483)

SKU:
STJA0006483
£49.00 - £261.00
Processing The item has been added

Short Description :Rabbit polyclonal anti-Rab effector MyRIP (591-641) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:1000-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:MYRIP
Gene ID:25924
Uniprot ID:MYRIP_HUMAN
Immunogen:Synthesized peptide derived from human MYRIP AA range: 591-641
Immunogen Region:591-641
Specificity:This antibody detects endogenous levels of human MYRIP
Function Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release.
Protein Name Rab Effector Myrip
Exophilin-8
Myosin-Viia- And Rab-Interacting Protein
Synaptotagmin-Like Protein Lacking C2 Domains C
Slac2-C
Slp Homolog Lacking C2 Domains C
Database Links Reactome: R-HSA-264876
Reactome: R-HSA-9824585
Cellular Localisation Cytoplasm
Perinuclear Region
Cytoplasmic Vesicle
Secretory Vesicle
In Presynaptic And Postsynaptic Areas In Photoreceptor Cells And In The Basal Microvilli Of Retinal Pigment Epithelium Cells
Associated With Melanosomes
Colocalizes With Actin Filaments
Alternative Antibody Names Anti-Rab Effector Myrip antibody
Anti-Exophilin-8 antibody
Anti-Myosin-Viia- And Rab-Interacting Protein antibody
Anti-Synaptotagmin-Like Protein Lacking C2 Domains C antibody
Anti-Slac2-C antibody
Anti-Slp Homolog Lacking C2 Domains C antibody
Anti-MYRIP antibody
Anti-SLAC2C antibody

Information sourced from Uniprot.org