| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-myotilin (209-221) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 60kDa band observed in Human Skeletal Muscle lysates (calculated MW of 55.4kDa according to NP_006781.1. Recommended concentration: 0.1-0.3µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | MYOT |
| Gene ID: | 9499 |
| Uniprot ID: | MYOTI_HUMAN |
| Immunogen Region: | 209-221 |
| Accession Number: | NP_006781.1; NP_001129412.1 |
| Specificity: | This antibody is expected to recognize both reported isoforms (NP_006781.1; NP_001129412.1). |
| Immunogen Sequence: | DSQQHNSEHARLQ |
| Function | Component of a complex of multiple actin cross-linking proteins. Involved in the control of myofibril assembly and stability at the Z lines in muscle cells. |
| Protein Name | Myotilin57 Kda Cytoskeletal ProteinMyofibrillar Titin-Like Ig Domains ProteinTitin Immunoglobulin Domain Protein |
| Cellular Localisation | Cell MembraneSarcolemmaCytoplasmCytoskeletonMyofibrilSarcomereZ LineSarcomericAlso Localized To The SarcolemmaColocalizes With Myoz1 At The Z-Lines In Skeletal Muscle |
| Alternative Antibody Names | Anti-Myotilin antibodyAnti-57 Kda Cytoskeletal Protein antibodyAnti-Myofibrillar Titin-Like Ig Domains Protein antibodyAnti-Titin Immunoglobulin Domain Protein antibodyAnti-MYOT antibodyAnti-TTID antibody |
Information sourced from Uniprot.org